Polish clinical practice guideline on hyperthermic intraperitoneal chemotherapy (HIPEC) with cytoreductive surgery in peritoneal malignancy treatment

The management of peritoneal surface malignancy is a significant clinical problem in oncology. It was demonstrated that the combination of complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) may lead to long-term control of the disease or improved survival in select...

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Published in:Current Gynecologic Oncology 2014-08, Vol.12 (2), p.86-97
Main Authors: Rutkowski, Piotr, Śpiewankiewicz, Beata, Herman, Krzysztof, Jastrzębski, Tomasz, Kładny, Józef, Kojs, Zbigniew, Krzakowski, Maciej, Polkowski, Wojciech, Wyrwicz, Lucjan, Wysocki, Piotr, Zdzienicki, Marcin, Zegarski, Wojciech
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Language:eng ; pol
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Cancer
Chemotherapy
Clinical practice guidelines
Gastric cancer
Metastasis
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container_title Current Gynecologic Oncology
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creator Rutkowski, Piotr
Śpiewankiewicz, Beata
Herman, Krzysztof
Jastrzębski, Tomasz
Kładny, Józef
Kojs, Zbigniew
Krzakowski, Maciej
Polkowski, Wojciech
Wyrwicz, Lucjan
Wysocki, Piotr
Zdzienicki, Marcin
Zegarski, Wojciech
description The management of peritoneal surface malignancy is a significant clinical problem in oncology. It was demonstrated that the combination of complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) may lead to long-term control of the disease or improved survival in selected patients. The aim of this paper was to present the optimal indications and technical guidelines for performing HIPEC in Poland. The application of this method requires experience of a multidisciplinary team of physicians (gynecologic oncologist, surgeon and clinical oncologist), availability of diagnostic and therapeutic resources (intensive care unit) as well as a dedicated perfusion system. A crucial aspect for obtaining optimal treatment outcomes is the selection of patients. Such a selection takes place both at the beginning of treatment and intraoperatively. The initial selection of patients qualified for HIPEC includes ruling out extraperitoneal spread of cancer and metastases to the liver (single resectable liver metastases in patients with colorectal carcinoma are not contraindications) and lungs. According to current international guidelines, the HIPEC procedure is a standard treatment in patients with ovarian carcinoma that metastasizes to the peritoneum, in colorectal cancer, when PCI
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subjects Cancer
Chemotherapy
Clinical practice guidelines
Gastric cancer
Metastasis
title Polish clinical practice guideline on hyperthermic intraperitoneal chemotherapy (HIPEC) with cytoreductive surgery in peritoneal malignancy treatment
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