Moderating effects of social support on the relationship between substance use disorders and HIV viral load and medication adherence among Black women living with HIV in the United States

Substance use may predict lower rates of antiretroviral therapy (ART) adherence and viral suppression among Black Women Living with HIV (BWLWH). We assessed how perceived social support (PSS) moderates the relationship between substance use disorder (SUD) and viral load (VL) and ART adherence. 119 B...

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Bibliographic Details
Published in:AIDS care 2022-10, Vol.34 (10), p.1219-1228
Main Authors: Reid, Rachelle, Dale, Sannisha K.
Format: Article
Language:English
Subjects:
Adherence
Alcohol related disorders
Alcohol use
Alcoholism
Anti-HIV Agents - therapeutic use
Anti-Retroviral Agents - therapeutic use
Antiretroviral agents
Antiretroviral therapy
Black people
Black women
Drugs
Female
Friendship
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
Human immunodeficiency virus
Humans
Medication Adherence
Patient compliance
Perceived social support
Significant others
Social interactions
Social Support
Substance use
Substance use disorder
Substance-Related Disorders - drug therapy
Substance-Related Disorders - epidemiology
United States - epidemiology
Viral Load
Women
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Summary:Substance use may predict lower rates of antiretroviral therapy (ART) adherence and viral suppression among Black Women Living with HIV (BWLWH). We assessed how perceived social support (PSS) moderates the relationship between substance use disorder (SUD) and viral load (VL) and ART adherence. 119 BWLWH provided information on PSS, SUD, alcohol use disorder (AUD) and adherence (via Wisepill). Higher PSS from friends (β = −.263, p = .008) and significant others (β = −.219, p = .025) predicted lower VL. SUD predicted low Wisepill adherence (a) in the past week (β = −.273, p = .035) and past two weeks (β = −.273, p = .033) only for women low in PSS from friends, and (b) in the past two weeks only for women low in total PSS (β = −.294, p = .024). Ironically, for women high in total PSS, SUD predicted higher adherence in the past four weeks (β = .360, p = .006). Adherence and VL may be bolstered by understanding the role of various forms of PSS and SUDs.
ISSN:0954-0121
1360-0451
1360-0451
DOI:10.1080/09540121.2021.2001415