Evolution of RAS Mutations in Cell-Free DNA of Patients with Tissue RAS Wild-Type Metastatic Colorectal Cancer Receiving First-Line Treatment: The PERSEIDA Study

The serial analysis of cell-free DNA (cfDNA) enables minimally invasive monitoring of tumor evolution, providing continuous genetic information. PERSEIDA was an observational, prospective study assessing the cfDNA RAS (KRAS/NRAS) mutational status evolution in first-line, metastatic CRC, RAS wild-ty...

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Bibliographic Details
Published in:Cancers 2022-12, Vol.14 (24), p.6075
Main Authors: Valladares-Ayerbes, Manuel, Garcia-Alfonso, Pilar, Muñoz Luengo, Jorge, Pimentel Caceres, Paola Patricia, Castillo Trujillo, Oscar Alfredo, Vidal-Tocino, Rosario, Llanos, Marta, Llorente Ayala, Beatriz, Limon Miron, Maria Luisa, Salud, Antonieta, Cirera Nogueras, Luis, Garcia-Carbonero, Rocio, Safont, Maria Jose, Falco Ferrer, Esther, Aparicio, Jorge, Vicente Conesa, Maria Angeles, Guillén-Ponce, Carmen, Garcia-Teijido, Paula, Medina Magan, Maria Begoña, Busquier, Isabel, Salgado, Mercedes, Lloansí Vila, Ariadna
Format: Article
Language:English
Subjects:
Alleles
Biopsy
Cancer therapies
Chemotherapy
Clinical medicine
Colorectal cancer
Colorectal carcinoma
Deoxyribonucleic acid
DNA
Evolution
Metastases
Metastasis
Mutants
Mutation
Patients
Plasma
Tumors
Variables
Womens health
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