513 Young patients with hypersomnia at Tufts Medical Center

• Published in: Sleep (New York, N.Y.) N.Y.), 2021-05, Vol.44 (Supplement_2), p.A202-A202
• Main Authors: Oster, Joel, Jost-Price, Emma, Tucker, Matthew, Grover, Aarti
• Format: Article
• Language: English
• Subjects: Comorbidity; Patients; Sleep apnea; Sleep disorders
• ISSN: 0161-8105; 1550-9109
• DOI: 10.1093/sleep/zsab072.512

Introduction Young people with hypersomnia (up to 30 years old) represent unique clinical patients that are relatively unstudied. This population has complex presentations, may have increased utilization of medical resources, and have additional and or untreated comorbid conditions such as mild OSA (Obstructive Sleep Apnea). This project looks to characterize and inventory clinical variables of this subset of sleep medicine patients at Tufts Medical Center. In addition, we seek to tabulate management of these patients in order to specifically delineate whether or not treating mild OSA in this group resulted in clinical improvement. Methods After IRB approval, a retrospective database was used to search for patients up to age 30 with comorbid hypersomnia diagnoses from 5/1/2015 to 12/2020. De-indentified datasets, including multiple clinical variables and demographics were analyzed and compared to an age-matched control group of patients who also included an OSA diagnosis. Results Various clinical and demographic data sets were collected in the hypersomnia patient population to characterize the quality and nature of their sleep and hospital utilization. Our preliminary results for this sub-population of 96 patients have found that on average these patients had 2.16 visits to our medical center with some outliers with as many as 6–10 visits in a two-year period from the initial contact. This group had a mean WASO (Wake After Sleep Onset) of 48.95 minutes, a mean sleep latency of 8.56 minutes, and a mean amount of stage N1 sleep of 25.6 minutes (6.4%). Further research will be done to compare these values and more to a similar population with OSA. Conclusion Our retrospective review identifies clinically important data relevant to the sleep quality, patient management, and resource utilization of young patients with hypersomnia. Further research with a comparison to a control group with OSA may identify important differences or nuances between these groups. Support (if any) None