Non‐negative matrix factorisation of Raman spectra finds common patterns relating to neuromuscular disease across differing equipment configurations, preclinical models and human tissue

Raman spectroscopy shows promise as a biomarker for complex nerve and muscle (neuromuscular) diseases. To maximise its potential, several challenges remain. These include the sensitivity to different instrument configurations, translation across preclinical/human tissues and the development of multi...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Raman spectroscopy 2023-03, Vol.54 (3), p.258-268
Main Authors: Alix, James J. P., Plesia, Maria, Schooling, Chlöe N., Dudgeon, Alexander P., Kendall, Catherine A., Kadirkamanathan, Visakan, McDermott, Christopher J., Gorman, Gráinne S., Taylor, Robert W., Mead, Richard J., Shaw, Pamela J., Day, John C.
Format: Article
Language:English
Subjects:
Accuracy
amyotrophic lateral sclerosis
Animal models
Biomarkers
Configurations
data analysis
Disease
Duchenne's muscular dystrophy
Dystrophy
Factorization
Feature extraction
Human tissues
Mitochondria
Muscles
Muscular dystrophy
neuromuscular disease
Neuromuscular diseases
non‐negative matrix factorisation
Raman spectra
Raman spectroscopy
Spectroscopy
Spectrum analysis
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!