Moving Forward with GMP 3D Printing for Drug Products

NIR is used to measure mixture homogeneity, and a photographic monitoring system identifies the physical properties of the tablets; nonconforming tablets can be automatically eliminated. ln-blister printing Aprecia Pharmaceuticals has launched a small-footprint 3DP technology that uses binder jettin...

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Bibliographic Details
Published in:Pharmaceutical technology Europe 2022-12, Vol.34 (12), p.21-23
Main Author: Markarian, Jennifer
Format: Article
Language:English
Subjects:
Blister packs
Design
Good Manufacturing Practice
Pharmaceuticals
Online Access:Get full text
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Summary:NIR is used to measure mixture homogeneity, and a photographic monitoring system identifies the physical properties of the tablets; nonconforming tablets can be automatically eliminated. ln-blister printing Aprecia Pharmaceuticals has launched a small-footprint 3DP technology that uses binder jetting to form 3D-printed tablets directly in blister packaging cavities. Forming the tablet directly in the blister packaging offers several benefits, one of which is the ability to eliminate material waste and produce yields of 99%, reports Smith. Another benefit is flexibility-each individual blister cavity can have a custom formulation and tablet volume/size. The Z-Form Flex platform is designed for a wide range of production volumes, from one blister pack up to 2000 to 3000 finished blister package units/hr, with minimal to no scale-up.
ISSN:1753-7967