Effects of Smoking Cessation on Peak Nasal Inspiratory Flow and Nasal Mucociliary Clearance

Introduction: In this study, the aim was to investigate smoking cessation on peak nasal inspiratory flow (PNIF) and nasal mucociliary clearance (MCC). Methods: Sixty-two (32 male and 30 female) smokers were included in this prospective study. Varenicline (Champix[R], R-Pharm, Germany) was prescribed...

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Bibliographic Details
Published in:Istanbul medical journal 2022-08, Vol.23 (3), p.174-178
Main Authors: Cakan, Dogan, Usaklioglu, Semih
Format: Article
Language:English
Subjects:
Analysis
Chronic illnesses
Disease
Drug withdrawal
Endoscopy
Health care
Medical diagnosis
mucociliary clearance
nasal obstruction/diagnosis
Nicotine
Nose
nose/physiology
Otolaryngology
Respiration
saccharin/pharmacokinetics
smoking
Smoking and women
Smoking cessation
Smoking cessation programs
Test methods
Tobacco
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Summary:Introduction: In this study, the aim was to investigate smoking cessation on peak nasal inspiratory flow (PNIF) and nasal mucociliary clearance (MCC). Methods: Sixty-two (32 male and 30 female) smokers were included in this prospective study. Varenicline (Champix[R], R-Pharm, Germany) was prescribed to all subjects who want to quit smoking as supportive therapy. Three-month treatment is planned. Day 0 (baseline), 3rd month (after smoking cessation), and 6 h (3 months after smoking cessation) PNIF values with decongestant (PNIFwD) and without decongestant (PNIFsD) and nasal mucociliary clearance time (MCT) with the saccharine test were determined. The acquired data were evaluated statistically. Results: The mean age of the subjects was 36.77 [+ or -] 9.63 (minimum: 18, maximum: 60) years. Significant differences were found between the PNIF and MCT values during different study periods (p
ISSN:2619-9793
1304-8503
2148-094X
DOI:10.4274/imj.galenos.2022.69077