Polymer Cu2+ and Ag+ furancarboxylate complexes with 4,4’-bipyridine: synthetic approaches, structure, thermal behavior, and biological activity

• Published in: Russian chemical bulletin 2023-08, Vol.72 (8), p.1894-1904
• Main Authors: Koshenskova, K. A., Baravikov, D. E., Khoroshilov, A. V., Nelyubina, Yu. V., Primakov, P. V., Bekker, O. B., Dokuchaeva, K. S., Dolgushin, F. M., Kiskin, M. A., Eremenko, I. L., Lutsenko, I. A.
• Format: Article
• Language: English
• Subjects: Acetates; Atomic properties; Biological activity; Chemical synthesis; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Coordination numbers; Copper; Decarboxylation; Full Articles; Hydrogen bonds; Inorganic Chemistry; Metal oxides; Organic Chemistry; Polymers; Silver; Thermal analysis; Thermodynamic properties; X-ray diffraction
• ISSN: 1066-5285; 1573-9171
• DOI: 10.1007/s11172-023-3974-z

Polymer complexes of the composition {[Cu 2 (fur) 4 (bpy)] n • n MeOH} ( 1 ) and {[Ag 3 (fur)(bpy) 4 ] n •2 n fur·13.5nH 2 O} ( 2 ) were synthesized by the reactions of copper(ii) and silver(i) acetates, respectively, with anions of furancarboxylic acid (Hfur) and 4,4’-bi-pyridine (bpy) under different synthesis conditions. The structures of the new complexes were established by X-ray diffraction (XRD) analysis. According to the XRD data, complex 1 is a polymer, in which the molecular metal oxide moieties are connected in a monodentate manner through bpy to form a 1D structural motif. The coordination environment of the copper(ii) atom in complex 1 can be described as a square pyramid {CuO 4 N}; the coordination number is 5. ionic complex 2 contains three nonequivalent Ag i atoms in different coordination environment with different coordination numbers of the complexing metal (CN Ag(1) = 4; CN Ag(2)Ag(3) = 2). The supramolecular level of complex 2 is a 3D structure stabilized by different types of interactions, such as hydrogen bonds, π-stacking and ar-gentophilic interactions. The simultaneous thermal analysis demonstrated that complex 1 undergoes desolvation and decarboxylation at temperatures below 234 °C, whereas the bipyridine moieties coordinated to the copper(ii) atoms are not completely eliminated even at 500 °C. The in vitro biological activity of complexes 1 and 2 was evaluated against the non-pathogenic mycobacterial strain Mycolicibacterium smegmatis .