Enantiospecific Total Synthesis of (−)‐Hyacinthacine A1 and (+)‐Hyacinthacine A1 and Their Homologues Using Nitrogen Substituted Donor–Acceptor Cyclopropane

A concise and efficient enantiospecific total synthesis of (−)‐hyacinthacine A1 and (+)‐hyacinthacine A1 was achieved from commercially available starting material L‐pyroglutamic acid and D‐glutamic acid, respectively. For the synthesis of this trihydroxylated pyrrolizidine ring, we employed the nit...

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Bibliographic Details
Published in:European journal of organic chemistry 2023-11, Vol.26 (41)
Main Authors: Gharpure, Santosh J, Patel, Raj K
Format: Article
Language:English
Subjects:
Cyclopropane
Glutamic acid
Nitrogen
Regioselectivity
Ring opening
Substitutes
Synthesis
Online Access:Get full text
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