P31 Food allergy prevalence in cystic fibrosis patients

BackgroundCystic fibrosis (CF) is a complex disorder with multisystem involvement. Although we used to believe that an association between CF and food allergies is rare and more frequently a false diagnostic, in the late years, as food allergies’ prevalence is rising, the association between these t...

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Published in:Archives of disease in childhood 2017-06, Vol.102 (Suppl 2), p.A47-A47
Main Authors: Craiu, Mihai, Comanici, Valentina, Vasile, Ana Maria, Codreanu, Ioana, Delia, Corina, Buia, Mariana, Nicoleta, Lacatus, Stan, Iustina
Format: Article
Language:English
Subjects:
Allergies
Allergy
Bovine serum albumin
Casein
Celiac disease
Comorbidity
Cystic fibrosis
Food
Food allergies
Lactalbumin
Nutrition
Nutritional status
Patients
Pediatrics
Proton pump inhibitors
Wheat
β-Lactoglobulin
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Summary:BackgroundCystic fibrosis (CF) is a complex disorder with multisystem involvement. Although we used to believe that an association between CF and food allergies is rare and more frequently a false diagnostic, in the late years, as food allergies’ prevalence is rising, the association between these two disorders is becoming more common.Aimthe aim of the study was to determine food allergy prevalence in cystic fibrosis patients treated at the Mother and Child Care Institute ‘Alessandrescu-Rusescu’ between 2011–2016.Methodwe conducted a five years retrospective study between 2011–2016 on 68 cystic fibrosis patients. Age of CF diagnostic was between 2 months and 10 years. We followed the cases with poor nutritional status despite PERT and proton pump inhibitors therapy and the association with cutaneous manifestations. We performed allergen specific IgE antibody test (lactalbumin, casein, beta lactoglobulin, egg, carrot, soya, nut, peanut, wheat, bovine serum albumin).Results8 out of 68 CF patients treated in our centre had food allergies, with a 11,76% prevalence. 6 of them have milk protein allergy, 1 with egg white allergy and 1 patient with multiple allergies (milk protein, egg, wheat, peanuts).Conclusionit is important to further investigate possible comorbidities in CF patients with poor nutritional status and persistent digestive symptomatology despite adequate nutrition and adherence to PERT therapy. Food allergies seem to be one of the most frequent associations, surpassing celiac disease. Treatment conduct and nutritional recovery in these cases represent a milestone even for experienced clinicians.
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2017-313273.119