Testosterone-mediated activation of androgenic signaling sustains in vitro the transformed and radioresistant phenotype of rhabdomyosarcoma cell lines

• Published in: Sport sciences for health 2018-08, Vol.14 (2), p.433-438
• Main Authors: Cabistany, Leo, Coswig, Victor Silveira, Orcy, Rafael Bueno, Del Vecchio, Fabricio Boscolo
• Format: Article
• Language: English
• Subjects: Anaerobic threshold; Athletes; Combat sports; Data collection; Exercise; Human Physiology; Jumping; Martial arts; Medicine; Medicine & Public Health; Metabolic Diseases; Original Article; Regression analysis; Rhabdomyosarcoma; Sports Medicine
• ISSN: 1824-7490; 1825-1234
• DOI: 10.1007/s11332-018-0439-0

Objective This study aimed to analyze the effects of Taekwondo match on blood and salivary lactate concentration, and their correlations, pre- and post-Taekwondo matches. Methods For that eleven Taekwondo fighters (18 ± 3.6 years old, 59.18 ± 14.2 kg, 1.61 ± 0.1 cm, and 70.81 ± 97.4 months of practice) were enrolled. An experimental study with pre- and post-match measures was conduct were blood and salivary lactate measured, as well as vertical height and rating of perceived exertion. For data analysis Student’s t test, Pearson’s coefficient and linear regressions were applied using SPSS software version 22.0 and statistical significance was set in 5%. Results Blood and salivary lactate measures changed significantly from PRE to POST ( p  = 0.001 and p  = 0.04, respectively) with large and moderate effects, respectively. Correlations between lactate measures did not show significance ( r  = 0.35; p  = 0.39). Otherwise, POST values showed moderate significant correlations ( r  = 0.61; p  = 0.04). Additionally, linear regressions indicated that POST blood lactate concentrations can explain only 37.8% of POST salivary lactate concentrations ( p  = 0.04). Conclusion To conclude, blood and salivary lactate responses do not present similar responses for TKD athletes after combat simulation.