The evolution of pediatric soft‐tissue free flap reconstruction of the lower extremity after oncologic resection: A 30year experience

• Published in: Microsurgery 2024-01, Vol.44 (1)
• Main Authors: Cohen, Zack, Plotsker, Ethan, Graziano, Francis, Cordeiro, Peter, Disa, Joseph, Mehrara, Babak, Fabbri, Nicola, Azoury, Saïd C, Farooq Shahzad
• Format: Article
• Language: English
• Subjects: Complications; Demographics; Evolution; Microvasculature; Osteosarcoma; Patients; Pediatrics; Postoperative; Reconstruction; Reconstructive surgery; Sarcoma; Thigh; Tumors
• ISSN: 0738-1085; 1098-2752
• DOI: 10.1002/micr.31130

IntroductionLimb salvage has become the standard of care for lower extremity tumors because of improvements in adjuvant treatments and reconstructive techniques. While there is literature assessing pediatric lower extremity free flap reconstruction in the setting of trauma, there is a paucity of literature that analyzes oncologic free flap reconstruction in this patient population. We report our long‐term experience and evolution of care for lower extremity oncologic free flap reconstruction in pediatric patients.MethodsThis is a retrospective case series of all patients ≤18 years of age who underwent oncologic soft‐tissue microvascular reconstruction of the lower extremity, from 1992 to 2021. Data were collected for patient demographics, oncologic treatment, operative details, and post‐operative outcomes. Functional outcomes were assessed by weight bearing status, ambulation, and participation in activities‐of‐daily‐living (ADLs), and musculoskeletal tumor society (MSTS) scores.ResultsOver the 30‐year study period, inclusion criteria were met by 19 patients (11 males, 8 females) with a mean age of 13.8 years and a mean follow‐up of 5.3 years. At last follow‐up, 13 patients (68.5%) were alive. The most common pathology was osteogenic sarcoma (13 patients, 68.5%). Sites of reconstruction were the hip (n = 1), thigh (n = 5), knee (n = 4), leg (n = 7), and the foot (n = 2). The most commonly used flaps were latissimus dorsi (n = 8), gracilis (n = 4), and anterolateral thigh ± vastus (n = 4). Postoperative complications occurred in nine patients (43%). Overall flap success rate was 95%. At latest follow‐up, ambulation without assistive device was obtained in 11 patients (58%), full weight bearing was achieved by 13 patients (68.5%), and ADLs could be performed independently by 13 patients (68.5%). Mean MSTS score was 23.1/30.ConclusionMicrovascular reconstruction for oncological lower extremity defects in the pediatric population has high limb salvage rates and good functional outcomes.