Mild Sleep-Disordered Breathing and Cardiovascular Disease Risk

Purpose of Review Sleep-disordered breathing, particularly obstructive sleep apnea (OSA), was identified to impact several health outcomes and physiopathological processes, most notably cardiovascular disease (CVD). However, much less research had addressed the impact of mild OSA as a risk factor fo...

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Bibliographic Details
Published in:Current sleep medicine reports 2019-12, Vol.5 (4), p.225-233
Main Authors: Zeineddine, Salam, Martin, Jennifer L., Badr, M. Safwan
Format: Article
Language:English
Subjects:
Antihypertensives
Blood pressure
Body mass index
Cardiac arrhythmia
Cardiology
Cardiovascular disease
Chronic illnesses
Cohort analysis
Comorbidity
Coronary vessels
Drug dosages
Family Medicine
General Practice
Heart Disease and Sleep Disturbances (R Khayat
Heart failure
Hypertension
Hypoxia
Insomnia
Internal Medicine
Longitudinal studies
Medicine
Medicine & Public Health
Neurology
Otorhinolaryngology
Psychiatry
Section Editor
Sleep apnea
Sleep disorders
Topical Collection on Heart Disease and Sleep Disturbances
Vein & artery diseases
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Summary:Purpose of Review Sleep-disordered breathing, particularly obstructive sleep apnea (OSA), was identified to impact several health outcomes and physiopathological processes, most notably cardiovascular disease (CVD). However, much less research had addressed the impact of mild OSA as a risk factor for symptomatic CVD. The purpose of this review is to assess the evidence regarding mild OSA and its association with CVD and whether treatment of mild OSA is effective at preventing adverse cardiovascular outcomes. Recent Findings There is absence of recent large-scale randomized clinical trials that address the impact of mild OSA and its therapy on the risk of CVD. Findings from recent studies are inconsistent and do not support the use of continuous positive airway pressure therapy for the sole purpose of preventing adverse cardiovascular outcomes in patients with mild OSA. Summary There is limited or uncertain evidence pertaining to the impact of mild OSA and its therapy on CVD. Future research is mandated to further elucidate this critical topic.
ISSN:2198-6401
2198-6401
DOI:10.1007/s40675-019-00162-x