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Evaluation of HbA1c levels as probable diagnostic of depression symptoms in Mexican individuals with type 2 diabetes mellitus

Background Depression is present in individuals with type 2 diabetes mellitus. Objective   We evaluated the sociodemographic, anthropometric, and clinical features of Mexican individuals with clinical depressive symptoms in order to identify predictors for depression symptoms; finally, we evaluated...

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Published in:International journal of diabetes in developing countries 2024-09, Vol.44 (3), p.585-591
Main Authors: Juárez-Rojop, Isela Esther, Tovilla-Vidal, Gisselle, López-Narváez, María Lilia, Tovilla-Zárate, Carlos Alfonso, Rodríguez-Sánchez, Esther, González-Castro, Thelma Beatriz, Fresán, Ana, Ramírez-González, Dania, Hernández-Díaz, Yazmín
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Language:English
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Summary:Background Depression is present in individuals with type 2 diabetes mellitus. Objective   We evaluated the sociodemographic, anthropometric, and clinical features of Mexican individuals with clinical depressive symptoms in order to identify predictors for depression symptoms; finally, we evaluated if HbA1c levels could be used as a probable diagnostic of depressive symptoms in individuals with type 2 diabetes mellitus. Methods The population studied consisted of 376 Mexicans with diabetes who were interviewed to collect information about comorbidities and habits. The evaluation of depressive symptoms was performed using the Hamilton scale. For a possible clinical association between HbA1c levels and depressive symptoms, we performed chi-square tests ( χ 2 )/ t tests. A multivariate logistic regression model with the backward conditional method was used to identify predictors of depressive symptoms. An ROC curve was plotted to assess the possible role of HbA1c as a diagnostic predictive test of depression symptoms. Results A total of 42.8% ( n  = 161) individuals showed clinical depressive symptoms. When comparing individuals with and without depression symptoms, those with depression symptoms showed higher levels of glucose and HbA1c; additionally, gender ( p  = 0.04), age ( p  = 0.006), HbA1c ( p  
ISSN:0973-3930
1998-3832
DOI:10.1007/s13410-023-01232-1