Pain gets personal

By James Mitchell Crow For clinicians on the challenging front line of chronic pain treatment, the tale of a general-practice physician in Australia who sought specialist help for her chronic migraines will be all too familiar. "When we compared the EEGs of people with pain versus those with no...

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Bibliographic Details
Published in:Nature (London) 2024-09, Vol.633 (8031), p.S28-S30
Main Author: Crow, James Mitchell
Format: Article
Language:English
Subjects:
Accuracy
Artificial intelligence
Back pain
Biomarkers
Brain mapping
Chronic pain
Clinical trials
Consortia
Electroencephalography
Functional magnetic resonance imaging
Low back pain
Machine learning
Magnetic resonance
Magnetic resonance imaging
Medical research
Medicine
Migraine
Neuroimaging
Pain
Physicians
Proteomics
Statistical analysis
Stimulators
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Summary:By James Mitchell Crow For clinicians on the challenging front line of chronic pain treatment, the tale of a general-practice physician in Australia who sought specialist help for her chronic migraines will be all too familiar. "When we compared the EEGs of people with pain versus those with no pain, standard statistical analysis showed no difference," Saab says. The rithm could not only between EEGs from people with chronic lower back pain and healthy controls, but also between people with this pain who would benefit from a spinal-cord stimulator and those who wouldn't2. Researchers looking for pain biomarkers have used a range of methods, including functional magnetic resonance imaging (fMRI) brain scans, genomics and proteomics.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-024-03004-1