Medically relevant radioisotope production through low energy heavy ion reactions

The emission of auger electrons from 161 Ho makes it as a potential candidate for Auger electronic therapy. Despite several methods for its production are proposed, it remains scarcely available. Most of the direct methods using low-energy protons and deuterons beams result in a high content of radi...

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Bibliographic Details
Published in:Journal of radioanalytical and nuclear chemistry 2024-10, Vol.333 (10), p.4779-4785
Main Authors: Mahato, Rahul, Singh, Dharmendra, Sharma, Nitin, Sahoo, Rajesh K., Chhura, Lupteindu, Mahato, Amritraj, Giri, Pankaj K., Linda, Sneha B., Kumar, Harish, Ali, Rahbar, Tali, Suhail A., Kumar, Sushil, Ansari, M. Afzal, Kumar, R., Muralithar, S., Singh, R. P.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Deuterons
Diagnostic Radiology
Electron beams
Gamma rays
Hadrons
Heavy Ions
Holmium
Holmium isotopes
Impurities
Inorganic Chemistry
Ion beams
Nuclear Chemistry
Nuclear Physics
Physical Chemistry
Radioisotopes
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Summary:The emission of auger electrons from 161 Ho makes it as a potential candidate for Auger electronic therapy. Despite several methods for its production are proposed, it remains scarcely available. Most of the direct methods using low-energy protons and deuterons beams result in a high content of radionuclidic impurities. Hence, an alternative method for the production of 161 Ho has been proposed. Experimental excitation functions in 16 O induced reactions were measured with the activation method in the 69–100 MeV energy range on 154 Sm targets. To measure the cross-section data for producing 161 Ho, the stacked foil irradiation method along with high-resolution gamma-ray spectrometry was employed. The experimental data are compared with results of PACE4 and EMPIRE-3.2.2 theoretical codes. It was observed that the 161 Ho radioisotope is produced via incomplete fusion. The production route suggested has no impurities of Holmium isotopes.
ISSN:0236-5731
1588-2780
DOI:10.1007/s10967-024-09623-2