Visualizing sub-organellar lipid distribution using correlative light and electron microscopy

Lipids and proteins compartmentalize biological membranes into nanoscale domains which are crucial for signaling, intracellular trafficking and many other cellular processes. Studying nanodomain function requires the ability to measure protein and lipid localization at the nanoscale. Current methods...

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Bibliographic Details
Published in:bioRxiv 2025-01
Main Authors: Lennartz, H Mathilda, Khan, Suman, Böhlig, Kristin, Leng, Weihua, Elsner, Falk, Scher, Nadav, Wilsch-Bräuninger, Michaela, Ori Avinoam, Nadler, André
Format: Article
Language:English
Subjects:
Cell Biology
Electron microscopy
Endosomes
Intracellular signalling
Lipid rafts
Lipids
Localization
Microscopy
Protein transport
Protein turnover
Proteins
Sphingomyelin
Tubules
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