Serum and urine eosinophil-derived neurotoxin (EDN) levels predict biologic response in severe asthma

Eosinophils are crucial in allergic inflammation, and their correlation with asthma severity has made them a focal point in predicting treatment outcomes. Blood eosinophil count is a commonly utilized marker. However, its limitations have prompted alternative biomarker exploration, such as eosinophi...

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Bibliographic Details
Published in:The World Allergy Organization journal 2025-01, Vol.18 (1), p.100990, Article 100990
Main Authors: Kang, Yu Ri, Kim, Hyunkyoung, Lee, Chae Eun, Jung, Jae-Woo, Moon, Ji-Yong, Park, So Young, Kim, Sae-Hoon, Yang, Min-Suk, Kim, Byung Keun, Kwon, Jae-Woo, Park, Hye-Kyung, Nam, Young-Hee, Cho, Young-Joo, Lee, Taehoon, Adcock, Ian M., Bhavsar, Pank, Chung, Kian Fan, Kim, Tae-Bum
Format: Article
Language:English
Subjects:
ACT assessment
Allergic inflammation
Asthma
Biologic therapies
Biomarker
Biomarkers
Blood eosinophil counts
Body mass index
Bronchodilators
Clinical outcomes
Cytokines
Eosinophil-derived neurotoxin
Eosinophils
Exacerbation rates
Hay fever
Inflammation
Lung function
Proteins
Rhinitis
Urine
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