Cancer Evo–Dev: A Theory of Inflammation-Induced Oncogenesis

Chronic inflammation is a prerequisite for the development of cancers. Here, we present the framework of a novel theory termed as Cancer Evolution-Development ( Cancer Evo-Dev ) based on the current understanding of inflammation-related carcinogenesis, especially hepatocarcinogenesis induced by chro...

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Bibliographic Details
Published in:	Frontiers in immunology 2021-11, Vol.12, p.768098
Main Authors:	Liu, Wenbin, Deng, Yang, Li, Zishuai, Chen, Yifan, Zhu, Xiaoqiong, Tan, Xiaojie, Cao, Guangwen
Format:	Article
Language:	English
Subjects:	Adaptation, Physiological APOBEC Deaminases - physiology Apoptosis Cancer Carcinogenesis Cell differentiation Chronic Disease Chronic infection Disease prevention DNA glycosylase DNA repair Epithelial-Mesenchymal Transition Evolution Evolution, Molecular Genomes Hepatitis B Hepatitis B, Chronic - complications Humans Immunology Inflammation Inflammation - complications Interleukin 6 Liver cancer Liver Neoplasms - etiology Lymphocytes Metabolic syndrome Metabolism Microenvironments Mutagenesis Mutation Natural killer cells Neoplasms - drug therapy Neoplasms - etiology Physical activity Polymorphism Signal transduction Telomeres Tumor necrosis factor-TNF Tumorigenesis Uracil viral infection Viral infections Viruses
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