"Recovery of sensorimotor function after frontal cortex damage in rats: Evidence that the serial lesion effect is due to serial recovery": Correction

• Published in: Behavioral neuroscience 1989-02, Vol.103 (1), p.53-53
• Main Authors: de Castro, John M., Zrull, Mark C.
• Format: Article
• Language: English
• Subjects: Frontal Lobe; Rats; Recovery (Disorders); Theory Verification
• ISSN: 0735-7044; 1939-0084
• DOI: 10.1037/h0090458

Reports an error in "Recovery of sensorimotor function after frontal cortex damage in rats: Evidence that the serial lesion effect is due to serial recovery" by John M. de Castro and Mark C. Zrull ( Behavioral Neuroscience, 1988[Dec], Vol 102[6], 843-851). The plate for this article appears on page 996. The information should read, "Plate B. Photographs of the dorsal side of the brains showing the minimum (top) and maximum (bottom) extent of the lesion produced unilaterally in the sham group (left) and bilaterally in the single- and two-stage groups (right)." (The following abstract of the original article appeared in record 1989-28759-001.) Multiple-staged brain lesions produce fewer and smaller behavioral effects than single surgery (the serial lesion effect, SLE). Two hypotheses were tested: the reduced deficit hypothesis and the serial recovery hypothesis. Effects of lesions of the medial frontal cortex on sensorimotor behavior were investigated in 7 rats that received bilateral damage in single surgery, 16 in 2 unilateral stages separated by 3 wks, or 5 with unilateral damage followed 3 wks later by sham surgery. Unilateral damage produced deficits on the contralateral side in response to visual, tactile, and olfactory stimuli and impairments in roll-over and paw withdrawal responses. All impairments except visual placement recovered over the next 3 wks. A 2nd unilateral lesion on the contralateral side produced the same symptoms on the opposite side. Bilateral damage incurred in a single stage produced the same deficits on both sides. Because the effects of the 2nd unilateral lesion in the 2-stage group produced comparable contralateral effects to those produced in the single-stage group, but no reinstatement of ipsilateral deficits, the reduced deficit hypothesis was rejected. It was concluded that SLE occurred as a result of serial recovery of the deficits. (PsycInfo Database Record (c) 2020 APA, all rights reserved)