Clinical predictors of apnoea‐hypopnoea during propofol sedation in patients undergoing spinal anaesthesia

• Published in: Anaesthesia 2012-07, Vol.67 (7), p.755-759
• Main Authors: Kim, G. H., Lee, J. J., Choi, S. J., Shin, B. S., Lee, A. R., Lee, S. H., Kim, M. H.
• Format: Article
• Language: English
• Subjects: Adult; Aged; Anesthesia; Anesthesia, Spinal - adverse effects; Anesthesia, Spinal - methods; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Conscious Sedation - adverse effects; Conscious Sedation - methods; Humans; Hypnotics and Sedatives - adverse effects; Intraoperative Complications - chemically induced; Male; Medical sciences; Middle Aged; Physical Examination - methods; Predictive Value of Tests; Propofol - adverse effects; Prostate - surgery; Risk Factors; Severity of Illness Index; Sleep Apnea, Obstructive - chemically induced; Sleep Apnea, Obstructive - diagnosis; Urinary Bladder - surgery
• ISSN: 0003-2409; 1365-2044
• DOI: 10.1111/j.1365-2044.2012.07115.x

Summary This study assessed the relationship between the occurrence of apnoea‐hypopnoea during propofol sedation for spinal anaesthesia and two different predictive tests of sleep apnoea: the STOP‐Bang score (snoring while sleeping, daytime tiredness, observed breathing stoppages, high blood pressure–body mass index, age, neck circumference, gender); and the obstructive sleep apnoea (OSA) score. Thirty‐four middle‐aged men not diagnosed with obstructive sleep apnoea received propofol infusions adjusted to produce a bispectral index of 70–75. ApnoeaLinkTM was used to estimate the incidence of apnoea‐hypopnoea. The median (IQR [range]) apnoea‐hypopnoea index was 17 (8–24 [0–70]) events.h−1 and correlated weakly with the STOP‐Bang score (p = 0.022, r = 0.423) and moderately with the OSA score (p