The contribution of the dorsolateral prefrontal cortex to the preparation for deception and truth-telling

• Published in: Brain research 2012-06, Vol.1464, p.43-52
• Main Authors: Ito, Ayahito, Abe, Nobuhito, Fujii, Toshikatsu, Hayashi, Akiko, Ueno, Aya, Mugikura, Shunji, Takahashi, Shoki, Mori, Etsuro
• Format: Article
• Language: English
• Subjects: Anatomical correlates of behavior; Behavioral psychophysiology; Biological and medical sciences; brain; Brain Mapping; cortex; Deception; Dorsolateral prefrontal cortex; Executive function; Executive Function - physiology; Female; Functional MRI; Fundamental and applied biological sciences. Psychology; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neurology; Photic Stimulation; Prefrontal Cortex - physiology; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Task preparation; Truth Disclosure; Young Adult
• ISSN: 0006-8993; 1872-6240
• DOI: 10.1016/j.brainres.2012.05.004

Abstract Recent neuroimaging evidence suggests that the dorsolateral prefrontal cortex is associated with creating deceptive responses. However, the neural basis of the preparatory processes that create deception has yet to be explored. Previous neuroimaging studies have demonstrated that the preparation for a certain task activates brain areas relevant to the execution of that task, leading to the question of whether dorsolateral prefrontal activity is observed during the preparation for deception. In the present study, we used functional magnetic resonance imaging (fMRI) to determine whether dorsolateral prefrontal activity, which increases during the execution of deception compared with the execution of truth-telling, also increases during the preparation for deception compared with the preparation for truth-telling. Our data show that the execution of deception was associated with increased activity in several brain regions, including the left dorsolateral prefrontal cortex, compared with truth-telling, confirming the contribution of this region to the production of deceptive responses. The results also reveal that the preparations for both deception and truth-telling were associated with increased activity in certain brain regions, including the left dorsolateral prefrontal cortex. These findings suggest that the preparations for truth-telling and deception make similar demands on the brain and that the dorsolateral prefrontal activity identified in the preparation phase is associated with general preparatory processes, regardless of whether one is telling a lie or the truth.