Who Should Have or Not Have an Axillary Node Dissection with Breast Cancer?

There have been dramatic changes in the approach to the axilla in women with breast cancer over the last 100 years, reflecting the evolution in our understanding of the underlying tumor biology, reduced disease burden because of early detection, and advances in all breast cancer treatment modalities...

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Bibliographic Details
Published in:Advances in surgery (Chicago) 2012-09, Vol.46 (1), p.1-18
Main Authors: Williams, Richelle T., MD, Winchester, David P., MD, Yao, Katharine, MD, Winchester, David J., MD
Format: Article
Language:English
Subjects:
Axilla
Axillary lymph node dissection
Breast cancer
Breast Neoplasms - mortality
Breast Neoplasms - pathology
Contraindications
Female
Humans
Lymph Node Excision
Neoplasm Staging
Patient Selection
Sentinel Lymph Node Biopsy
Surgery
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Summary:There have been dramatic changes in the approach to the axilla in women with breast cancer over the last 100 years, reflecting the evolution in our understanding of the underlying tumor biology, reduced disease burden because of early detection, and advances in all breast cancer treatment modalities. The approach to the axilla needs to be individualized, much like the extent of surgery for the primary tumor. Axillary dissection remains an important intervention for patients with more locally advanced disease. However, in patients with early-stage breast cancer, in whom regional recurrence is extremely low, the added benefit of an ALND has yet to be confirmed.
ISSN:0065-3411
1878-0555
DOI:10.1016/j.yasu.2012.04.001