BLD10/CEP135 Is a Microtubule-Associated Protein that Controls the Formation of the Flagellum Central Microtubule Pair

Cilia and flagella are involved in a variety of processes and human diseases, including ciliopathies and sterility. Their motility is often controlled by a central microtubule (MT) pair localized within the ciliary MT-based skeleton, the axoneme. We characterized the formation of the motility appara...

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Published in:	Developmental cell 2012-08, Vol.23 (2), p.412-424
Main Authors:	Carvalho-Santos, Zita, Machado, Pedro, Alvarez-Martins, Inês, Gouveia, Susana M., Jana, Swadhin C., Duarte, Paulo, Amado, Tiago, Branco, Pedro, Freitas, Micael C., Silva, Sara T.N., Antony, Claude, Bandeiras, Tiago M., Bettencourt-Dias, Mónica
Format:	Article
Language:	English
Subjects:	Animals biogenesis Biological and medical sciences Cell differentiation, maturation, development, hematopoiesis Cell physiology Cell structures and functions centrioles cilia Cytoskeleton, cytoplasm. Intracellular movements Drosophila Drosophila melanogaster - cytology Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Flagella - metabolism flagellum Fundamental and applied biological sciences. Psychology human diseases Male Microscopy, Electron, Transmission Microtubule-Associated Proteins - metabolism microtubules Microtubules - metabolism Molecular and cellular biology Protein Binding Spermatogenesis
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