The role of HbA1c in the diagnosis of diabetes mellitus in Australia

Summary For many years, the diagnosis of diabetes has been made through the laboratory‐based measurement of fasting or random blood glucose levels, or using the oral glucose tolerance test. A glycated haemoglobin (HbA1c) level ≥ 6.5% (48 mmol/mol) is now also acceptable for diagnosing diabetes. Caut...

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Bibliographic Details
Published in:Medical journal of Australia 2012-08, Vol.197 (4), p.220-221
Main Authors: D'Emden, Michael C, Shaw, Jonathan E, Colman, Peter G, Colagiuri, Stephen, Twigg, Stephen M, Jones, Graham R D, Goodall, Ian, Schneider, Hans G, Cheung, N Wah
Format: Article
Language:English
Subjects:
Australia
Biological and medical sciences
Biomarkers - blood
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - diagnosis
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
General aspects
Glycated Hemoglobin A - metabolism
Humans
Indigenous health
Medical sciences
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Summary:Summary For many years, the diagnosis of diabetes has been made through the laboratory‐based measurement of fasting or random blood glucose levels, or using the oral glucose tolerance test. A glycated haemoglobin (HbA1c) level ≥ 6.5% (48 mmol/mol) is now also acceptable for diagnosing diabetes. Caution is needed in interpreting HbA1c test results in the presence of conditions affecting red blood cells or their survival time, such as haemoglobinopathies or anaemia.
ISSN:0025-729X
1326-5377
DOI:10.5694/mja12.10988