Striatal dopamine D2/D3 receptor binding in pathological gambling is correlated with mood-related impulsivity

Pathological gambling (PG) is a behavioural addiction associated with elevated impulsivity and suspected dopamine dysregulation. Reduced striatal dopamine D2/D3 receptor availability has been reported in drug addiction, and may constitute a premorbid vulnerability marker for addictive disorders. The...

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Bibliographic Details
Published in:NeuroImage (Orlando, Fla.) Fla.), 2012-10, Vol.63 (1), p.40-46
Main Authors: Clark, Luke, Stokes, Paul R., Wu, Kit, Michalczuk, Rosanna, Benecke, Aaf, Watson, Ben J., Egerton, Alice, Piccini, Paola, Nutt, David J., Bowden-Jones, Henrietta, Lingford-Hughes, Anne R.
Format: Article
Language:English
Subjects:
Addiction
Addictions
Adult
Affect
Age
Corpus Striatum - diagnostic imaging
Corpus Striatum - physiopathology
Dopamine
Female
Gambling
Gambling - diagnostic imaging
Gambling - physiopathology
Humans
Impulsive Behavior
Impulsivity
Male
Middle Aged
Neuroimaging
Neurosciences
Parkinson's disease
Positron-Emission Tomography - methods
Psychopharmacology
Receptors, Dopamine D2 - metabolism
Receptors, Dopamine D3 - metabolism
Statistics as Topic
Striatum
Studies
Substance abuse treatment
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