The future of susceptibility contrast for assessment of anatomy and function

The magnetic properties of tissues affect MR images and differences in magnetic susceptibility can be utilized to provide impressive image contrast. Specifically, phase images acquired with gradient echo MRI provide unique and superb contrast which reflects variations in the underlying tissue compos...

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Bibliographic Details
Published in:NeuroImage (Orlando, Fla.) Fla.), 2012-08, Vol.62 (2), p.1311-1315
Main Author: Reichenbach, Jürgen R.
Format: Article
Language:English
Subjects:
Animals
Brain - anatomy & histology
Brain - physiology
Brain Mapping - history
Brain Mapping - methods
Brain Mapping - trends
Brain research
Data processing
History, 20th Century
History, 21st Century
Humans
Image Enhancement - methods
Image Processing, Computer-Assisted - history
Image Processing, Computer-Assisted - methods
Image Processing, Computer-Assisted - trends
Magnetic fields
Magnetic resonance imaging
Magnetic Resonance Imaging - history
Magnetic Resonance Imaging - methods
Magnetic Resonance Imaging - trends
Magnetic susceptibility
Magnetics
Magnetism
NMR
Nuclear magnetic resonance
Phase imaging
Quantitative susceptibility mapping
Studies
Susceptibility weighted imaging
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Description
Summary:The magnetic properties of tissues affect MR images and differences in magnetic susceptibility can be utilized to provide impressive image contrast. Specifically, phase images acquired with gradient echo MRI provide unique and superb contrast which reflects variations in the underlying tissue composition. There is great interest in extracting tissue susceptibility from image data since magnetic susceptibility is an intrinsic tissue property that reflects tissue composition much more closely than MRI phase. Still, this major tissue contrast mechanism is largely unexplored in magnetic resonance imaging because non-conventional reconstruction and dipole deconvolution are required to quantitatively map tissue susceptibility properly. This short review summarizes the current state of susceptibility contrast and susceptibility mapping and aims to identify future directions.
ISSN:1053-8119
1095-9572
DOI:10.1016/j.neuroimage.2012.01.004