Correlation of first-trimester fetal crown–rump length with outcome of pregnancy and birth weight

Abstract Objective To examine the association of crown–rump length (CRL) in the first trimester with low birth weight and adverse pregnancy outcome. Methods In a prospective cross-sectional study, CRL was measured in 876 healthy pregnant women undergoing ultrasound evaluation between 9 and 14 weeks...

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Bibliographic Details
Published in:International journal of gynecology and obstetrics 2012-11, Vol.119 (2), p.141-144
Main Authors: Vafaei, Homeira, Samsami, Alamtaj, Zolghadri, Jaleh, Hosseini-Nohadani, Azam
Format: Article
Language:English
Subjects:
Abortion
Adolescent
Adult
Biological and medical sciences
Birth Weight
Cross-Sectional Studies
Crown-Rump Length
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Infant, Low Birth Weight
Infant, Newborn
Low birth weight
Medical sciences
Middle Aged
Obstetrics and Gynecology
Pregnancy
Pregnancy Outcome
Pregnancy Trimester, First
Pregnancy. Fetus. Placenta
Prenatal Care - methods
Prospective Studies
Ultrasonography, Prenatal
Young Adult
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Summary:Abstract Objective To examine the association of crown–rump length (CRL) in the first trimester with low birth weight and adverse pregnancy outcome. Methods In a prospective cross-sectional study, CRL was measured in 876 healthy pregnant women undergoing ultrasound evaluation between 9 and 14 weeks of gestation. Birth weight and pregnancy outcomes were analyzed for the 544 participants who met the study criteria. Results Low (< 2500 g) and high (> 4000 g) birth weights were correlated with the difference between actual and expected CRL expressed in days of gestation, but no correlation was found between the difference between actual and expected CRL and premature delivery. Low birth weight ( P = 0.005) and abortion ( P = 0.03) were also correlated with the difference between actual and expected CRL. Conclusion Routinely measuring CRL during the first trimester to detect CRLs shorter than expected for gestational age could be useful to obstetricians. Anticipating a low birth weight and being warned about the possibility of abortion would enable them to manage prenatal care and delivery more appropriately.
ISSN:0020-7292
1879-3479
DOI:10.1016/j.ijgo.2012.05.040