The role of iron and zinc in chemotherapy-induced alopecia

Chemotherapy-induced alopecia is a common and distressing side effect in children with cancer. Iron and zinc are the well known trace elements which are associated with hair shedding. In this study, we investigated the hair content of iron and zinc in children with cancer consists of two groups: gro...

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Bibliographic Details
Published in:Journal of quantitative spectroscopy & radiative transfer 2005-10, Vol.95 (2), p.255-261
Main Authors: Buyukavci, Mustafa, Gurol, Ali, Karabulut, Abdulhalik, Budak, Gokhan, Karacan, Mehmet
Format: Article
Language:English
Subjects:
Alopecia
Cancer
Chemotherapy
Children
Control equipment
Hair
Iron
Patients
Zinc
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Summary:Chemotherapy-induced alopecia is a common and distressing side effect in children with cancer. Iron and zinc are the well known trace elements which are associated with hair shedding. In this study, we investigated the hair content of iron and zinc in children with cancer consists of two groups: group A, newly diagnosed patients; group B, the patients received a course of chemotherapy. We compared the results between each others and healthy controls. Hair content of iron and zinc was not different between the patient groups. Iron concentrations of patient samples, either at diagnosis or after chemotherapy, were significantly lower than healthy controls. However, there was no statistically significant difference between the groups regarding the zinc values. In conclusion, hair content of iron and zinc do not have a role in chemotherapy-induced alopecia.
ISSN:0022-4073
1879-1352
DOI:10.1016/j.jqsrt.2004.11.017