Does stenting of left-sided colorectal cancer as a “bridge to surgery” adversely affect oncological outcomes? A comparison with non-obstructing elective left-sided colonic resections

• Published in: International journal of colorectal disease 2012-11, Vol.27 (11), p.1509-1514
• Main Authors: Knight, Alexandra L., Trompetas, Vasileios, Saunders, Mike P., Anderson, Hugh J.
• Format: Article
• Language: English
• Subjects: Aged; Analysis; Cancer; Care and treatment; Colorectal cancer; Colorectal Neoplasms - surgery; Digestive System Surgical Procedures - adverse effects; Elective Surgical Procedures - adverse effects; Female; Gastroenterology; Health aspects; Hepatology; Humans; Internal Medicine; Kaplan-Meier Estimate; Male; Medicine; Medicine & Public Health; Mortality; Oncology, Experimental; Original Article; Proctology; Rankings; Stent (Surgery); Stents - adverse effects; Surgery; Treatment Outcome
• ISSN: 0179-1958; 1432-1262
• DOI: 10.1007/s00384-012-1513-8

Purpose With a theoretical link between stent insertion and increased risk of tumour seeding, there is concern about long-term survival after the use of self-expanding metallic stents (SEMS) as a “bridge to surgery” in the treatment of left-sided obstructing colorectal cancer. This cohort study aims to determine if preoperative stenting adversely affects long-term survival by comparing a group of patients having preoperative stenting (group A) with a group of patients having elective surgery (group B) in a single centre. Methods The study is retrospective. Survival was calculated with Kaplan–Meier analysis and compared using the log-rank test. Other group characteristics were compared with Fisher's exact test. Results From November 1998 to November 2008, 15 patients had preoperative SEMS and were entered in group A. This represented 11.5 % of a total of 130 patients undergoing SEMS insertion in the same period. Group B included 88 consecutive patients undergoing elective left-sided colonic resection for Dukes' B and C cancer excluding mid and low rectal tumours between January 2003 and December 2007. The 30-day mortality rate for groups A and B was 6.7 % (one patient) and 5.7 % (five patients), respectively. The 5-year survival rate was 60 % and 58 %, respectively, with a p value of 0.96. Conclusions In our own practice, patients undergoing SEMS as a “bridge to surgery” have the same long-term survival with those undergoing elective surgery. This finding needs to be confirmed in larger scale studies.