Self-monitoring of blood glucose (SMBG) improves glycaemic control in oral hypoglycaemic agent (OHA)-treated type 2 diabetes (SMBG-OHA study)

• Published in: Diabetes/metabolism research and reviews 2013-01, Vol.29 (1), p.77-84
• Main Authors: Harashima, Shin-ichi, Fukushima, Toru, Sasaki, Mayumi, Nishi, Yuichi, Fujimoto, Shimpei, Ogura, Masahito, Yamane, Shunsuke, Tanaka, Daisuke, Harada, Norio, Hamasaki, Akihiro, Nagashima, Kazuaki, Nakahigashi, Yuko, Seino, Yutaka, Inagaki, Nobuya
• Format: Article
• Language: English
• Subjects: Adult; Aged; Blood Glucose - analysis; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - drug therapy; Female; Glycated Hemoglobin A - metabolism; Humans; Hypoglycemic Agents - therapeutic use; Japan; Male; Middle Aged; palm puncture; Patient Compliance; Prospective Studies; self-monitoring of blood glucose (SMBG); Surveys and Questionnaires; type 2 diabetes
• ISSN: 1520-7552; 1520-7560
• DOI: 10.1002/dmrr.2363

Background We conducted a clinical research study to determine the effect of self‐monitoring of blood glucose (SMBG) on glycaemic control and the value of a putatively less painful blood sampling technique on SMBG in oral hypoglycaemic agent‐treated type 2 diabetes patients; SMBG has not been broadly applied in non‐insulin‐treated patients in Japan. Methods One hundred thirty‐seven subjects were recruited for the 24‐week, prospective, comparison study and randomized into three groups: 46, no SMBG group; 46, fingertip group; and 45, palm group. The primary endpoint was change in HbA1c. The secondary endpoints were SMBG compliance, dropout rate, treatment changes, and patient's and physician's satisfaction. Results Six subjects in the fingertip group (13.2%) and one subject in the palm group (2.2%) were dropped because of pain. A1C level of all subjects at 24‐week was decreased more in the fingertip (−0.23%) and palm (−0.16%) groups than that in the no SMBG group (+0.31%) (p