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Dermal Equivalents in Oncology: Benefit of One‐Stage Procedure
Background In oncology, dermal equivalent may be indicated to cover losses of substance related to skin tumors or after the removal of skin flaps. Objective To report our experience of two dermal equivalents, Matriderm 1 mm with a one‐stage graft (DE1) and Integra DL with a two‐stage graft (DE2) in...
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| Published in: | Dermatologic surgery 2013-01, Vol.39 (1pt1), p.43-50 |
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| container_end_page | 50 |
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| container_title | Dermatologic surgery |
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| creator | Pauchot, Julien Elkhyat, Ahmed Rolin, Gwenael Mac, Sophie Grumblat, Anne Fotso, Arnaud Humbert, Philippe Tropet, Yves |
| description | Background
In oncology, dermal equivalent may be indicated to cover losses of substance related to skin tumors or after the removal of skin flaps.
Objective
To report our experience of two dermal equivalents, Matriderm 1 mm with a one‐stage graft (DE1) and Integra DL with a two‐stage graft (DE2) in oncology.
Patients and Method
Retrospective, single‐center study involving 16 patients.
Results
Sixteen patients received dermal equivalents as an alternative to flaps (7 cases), over tendinous areas (7 cases), and for cosmetic purposes (2 cases). Twelve patients received DE1 and four DE2. Wound healing times with DE1 were 4 weeks less than those with DE2. Three cases of infection were noted with DE2. The use of dermal equivalents as an alternative to skin flaps was effective, and no adhesions were found over the tendinous areas.
Conclusion
The learning curve, the two‐stage graft required with DE2, and not using a vacuum‐assisted closure system can explain the high infection rate. The use of dermal equivalents is particularly indicated in the treatment of skin defect in oncology. The possibility of a one‐stage graft with DE1 and combination with negative pressure therapy is beneficial. |
| doi_str_mv | 10.1111/dsu.12044 |
| format | article |
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In oncology, dermal equivalent may be indicated to cover losses of substance related to skin tumors or after the removal of skin flaps.
Objective
To report our experience of two dermal equivalents, Matriderm 1 mm with a one‐stage graft (DE1) and Integra DL with a two‐stage graft (DE2) in oncology.
Patients and Method
Retrospective, single‐center study involving 16 patients.
Results
Sixteen patients received dermal equivalents as an alternative to flaps (7 cases), over tendinous areas (7 cases), and for cosmetic purposes (2 cases). Twelve patients received DE1 and four DE2. Wound healing times with DE1 were 4 weeks less than those with DE2. Three cases of infection were noted with DE2. The use of dermal equivalents as an alternative to skin flaps was effective, and no adhesions were found over the tendinous areas.
Conclusion
The learning curve, the two‐stage graft required with DE2, and not using a vacuum‐assisted closure system can explain the high infection rate. The use of dermal equivalents is particularly indicated in the treatment of skin defect in oncology. The possibility of a one‐stage graft with DE1 and combination with negative pressure therapy is beneficial.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1111/dsu.12044</identifier><identifier>PMID: 23190429</identifier><language>eng</language><publisher>United States</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chondroitin Sulfates - therapeutic use ; Collagen - therapeutic use ; Elastin - therapeutic use ; Head and Neck Neoplasms - surgery ; Humans ; Middle Aged ; Otorhinolaryngologic Neoplasms - surgery ; Reconstructive Surgical Procedures - methods ; Retrospective Studies ; Skin Neoplasms - surgery ; Skin Transplantation - methods ; Skin, Artificial ; Surgical Flaps ; Surgical Wound Infection - etiology ; Time Factors ; Wound Healing ; Young Adult</subject><ispartof>Dermatologic surgery, 2013-01, Vol.39 (1pt1), p.43-50</ispartof><rights>2012 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4654-758e1286126e0200afb2e70a67c8ee12cfb0e8161ee3ffbfd45f7c63f3d7b3513</citedby><cites>FETCH-LOGICAL-c4654-758e1286126e0200afb2e70a67c8ee12cfb0e8161ee3ffbfd45f7c63f3d7b3513</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fdsu.12044$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fdsu.12044$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23190429$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pauchot, Julien</creatorcontrib><creatorcontrib>Elkhyat, Ahmed</creatorcontrib><creatorcontrib>Rolin, Gwenael</creatorcontrib><creatorcontrib>Mac, Sophie</creatorcontrib><creatorcontrib>Grumblat, Anne</creatorcontrib><creatorcontrib>Fotso, Arnaud</creatorcontrib><creatorcontrib>Humbert, Philippe</creatorcontrib><creatorcontrib>Tropet, Yves</creatorcontrib><title>Dermal Equivalents in Oncology: Benefit of One‐Stage Procedure</title><title>Dermatologic surgery</title><addtitle>Dermatol Surg</addtitle><description>Background
In oncology, dermal equivalent may be indicated to cover losses of substance related to skin tumors or after the removal of skin flaps.
Objective
To report our experience of two dermal equivalents, Matriderm 1 mm with a one‐stage graft (DE1) and Integra DL with a two‐stage graft (DE2) in oncology.
Patients and Method
Retrospective, single‐center study involving 16 patients.
Results
Sixteen patients received dermal equivalents as an alternative to flaps (7 cases), over tendinous areas (7 cases), and for cosmetic purposes (2 cases). Twelve patients received DE1 and four DE2. Wound healing times with DE1 were 4 weeks less than those with DE2. Three cases of infection were noted with DE2. The use of dermal equivalents as an alternative to skin flaps was effective, and no adhesions were found over the tendinous areas.
Conclusion
The learning curve, the two‐stage graft required with DE2, and not using a vacuum‐assisted closure system can explain the high infection rate. The use of dermal equivalents is particularly indicated in the treatment of skin defect in oncology. The possibility of a one‐stage graft with DE1 and combination with negative pressure therapy is beneficial.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Chondroitin Sulfates - therapeutic use</subject><subject>Collagen - therapeutic use</subject><subject>Elastin - therapeutic use</subject><subject>Head and Neck Neoplasms - surgery</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Otorhinolaryngologic Neoplasms - surgery</subject><subject>Reconstructive Surgical Procedures - methods</subject><subject>Retrospective Studies</subject><subject>Skin Neoplasms - surgery</subject><subject>Skin Transplantation - methods</subject><subject>Skin, Artificial</subject><subject>Surgical Flaps</subject><subject>Surgical Wound Infection - etiology</subject><subject>Time Factors</subject><subject>Wound Healing</subject><subject>Young Adult</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp1kLtOwzAUQC0EoqUw8AMoIwxp_UqcMgFteUiVilQ6W45zXQXl0doJqBufwDfyJRgCbNzFV9dHZzgInRI8JH5GmWuHhGLO91CfRJSHXNBo3-9YxCGOCO2hI-eeMSZ0zPAh6lFGxpjTcR9dTcGWqghm2zZ_UQVUjQvyKlhUui7q9e4yuIEKTN4EtfFH-Hh7XzZqDcGjrTVkrYVjdGBU4eDk5x2g1e3saXIfzhd3D5Preah5HPFQRAkQmsSExoApxsqkFARWsdAJ-B9tUgwJiQkAMyY1GY-M0DEzLBMpiwgboPPOu7H1tgXXyDJ3GopCVVC3ThIqGMfM-z160aHa1s5ZMHJj81LZnSRYfgWTPpj8DubZsx9tm5aQ_ZG_hTww6oDXvIDd_yY5Xa465SfvNXSD</recordid><startdate>201301</startdate><enddate>201301</enddate><creator>Pauchot, Julien</creator><creator>Elkhyat, Ahmed</creator><creator>Rolin, Gwenael</creator><creator>Mac, Sophie</creator><creator>Grumblat, Anne</creator><creator>Fotso, Arnaud</creator><creator>Humbert, Philippe</creator><creator>Tropet, Yves</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201301</creationdate><title>Dermal Equivalents in Oncology: Benefit of One‐Stage Procedure</title><author>Pauchot, Julien ; Elkhyat, Ahmed ; Rolin, Gwenael ; Mac, Sophie ; Grumblat, Anne ; Fotso, Arnaud ; Humbert, Philippe ; Tropet, Yves</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4654-758e1286126e0200afb2e70a67c8ee12cfb0e8161ee3ffbfd45f7c63f3d7b3513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Chondroitin Sulfates - therapeutic use</topic><topic>Collagen - therapeutic use</topic><topic>Elastin - therapeutic use</topic><topic>Head and Neck Neoplasms - surgery</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Otorhinolaryngologic Neoplasms - surgery</topic><topic>Reconstructive Surgical Procedures - methods</topic><topic>Retrospective Studies</topic><topic>Skin Neoplasms - surgery</topic><topic>Skin Transplantation - methods</topic><topic>Skin, Artificial</topic><topic>Surgical Flaps</topic><topic>Surgical Wound Infection - etiology</topic><topic>Time Factors</topic><topic>Wound Healing</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pauchot, Julien</creatorcontrib><creatorcontrib>Elkhyat, Ahmed</creatorcontrib><creatorcontrib>Rolin, Gwenael</creatorcontrib><creatorcontrib>Mac, Sophie</creatorcontrib><creatorcontrib>Grumblat, Anne</creatorcontrib><creatorcontrib>Fotso, Arnaud</creatorcontrib><creatorcontrib>Humbert, Philippe</creatorcontrib><creatorcontrib>Tropet, Yves</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dermatologic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pauchot, Julien</au><au>Elkhyat, Ahmed</au><au>Rolin, Gwenael</au><au>Mac, Sophie</au><au>Grumblat, Anne</au><au>Fotso, Arnaud</au><au>Humbert, Philippe</au><au>Tropet, Yves</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dermal Equivalents in Oncology: Benefit of One‐Stage Procedure</atitle><jtitle>Dermatologic surgery</jtitle><addtitle>Dermatol Surg</addtitle><date>2013-01</date><risdate>2013</risdate><volume>39</volume><issue>1pt1</issue><spage>43</spage><epage>50</epage><pages>43-50</pages><issn>1076-0512</issn><eissn>1524-4725</eissn><abstract>Background
In oncology, dermal equivalent may be indicated to cover losses of substance related to skin tumors or after the removal of skin flaps.
Objective
To report our experience of two dermal equivalents, Matriderm 1 mm with a one‐stage graft (DE1) and Integra DL with a two‐stage graft (DE2) in oncology.
Patients and Method
Retrospective, single‐center study involving 16 patients.
Results
Sixteen patients received dermal equivalents as an alternative to flaps (7 cases), over tendinous areas (7 cases), and for cosmetic purposes (2 cases). Twelve patients received DE1 and four DE2. Wound healing times with DE1 were 4 weeks less than those with DE2. Three cases of infection were noted with DE2. The use of dermal equivalents as an alternative to skin flaps was effective, and no adhesions were found over the tendinous areas.
Conclusion
The learning curve, the two‐stage graft required with DE2, and not using a vacuum‐assisted closure system can explain the high infection rate. The use of dermal equivalents is particularly indicated in the treatment of skin defect in oncology. The possibility of a one‐stage graft with DE1 and combination with negative pressure therapy is beneficial.</abstract><cop>United States</cop><pmid>23190429</pmid><doi>10.1111/dsu.12044</doi><tpages>8</tpages></addata></record> |
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| ispartof | Dermatologic surgery, 2013-01, Vol.39 (1pt1), p.43-50 |
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| language | eng |
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| source | Wiley-Blackwell Journals |
| subjects | Adolescent Adult Aged Aged, 80 and over Chondroitin Sulfates - therapeutic use Collagen - therapeutic use Elastin - therapeutic use Head and Neck Neoplasms - surgery Humans Middle Aged Otorhinolaryngologic Neoplasms - surgery Reconstructive Surgical Procedures - methods Retrospective Studies Skin Neoplasms - surgery Skin Transplantation - methods Skin, Artificial Surgical Flaps Surgical Wound Infection - etiology Time Factors Wound Healing Young Adult |
| title | Dermal Equivalents in Oncology: Benefit of One‐Stage Procedure |
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