Acute Kidney Injury Following Bariatric Surgery

Background Postoperative acute kidney injury (AKI) following bariatric surgery has not been well studied. The aim of this study is to identify factors associated with risk of AKI. Methods The medical records of adult patients who underwent bariatric surgery between March 1, 2005 and March 31, 2011 a...

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Bibliographic Details
Published in:Obesity surgery 2013, Vol.23 (1), p.64-70
Main Authors: Weingarten, Toby N., Gurrieri, Carmelina, McCaffrey, Joan M., Ricter, Starla J., Hilgeman, Mandy L., Schroeder, Darrell R., Kendrick, Michael L., Greene, Eddie L., Sprung, Juraj
Format: Article
Language:English
Subjects:
Acute Kidney Injury - blood
Acute Kidney Injury - etiology
Acute Kidney Injury - therapy
Adult
Bariatric Surgery - adverse effects
Biomarkers - blood
Blood Transfusion
Case-Control Studies
Creatinine - blood
Dehydration - blood
Female
Gastrointestinal surgery
Glomerular Filtration Rate
Hospital Mortality
Humans
Kidneys
Logistic Models
Male
Medical Records
Medicine
Medicine & Public Health
Middle Aged
Obesity
Obesity, Morbid - blood
Obesity, Morbid - mortality
Obesity, Morbid - surgery
Original Contributions
Postoperative Complications
Predictive Value of Tests
Retrospective Studies
Risk Factors
Surgery
United States - epidemiology
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Summary:Background Postoperative acute kidney injury (AKI) following bariatric surgery has not been well studied. The aim of this study is to identify factors associated with risk of AKI. Methods The medical records of adult patients who underwent bariatric surgery between March 1, 2005 and March 31, 2011 at the Mayo Clinic were reviewed to identify patients who experienced AKI, defined as postoperative increase in serum creatinine (sCr) by 0.3 mg/dL within 72 h. For each AKI case, two controls were matched for surgical approach (laparotomy vs. laparoscopic). A chart review was conducted and conditional logistic regression analyses were performed to identify risk factors for AKI. Results There were 1,227 patients who underwent bariatric surgery, and of these, 71 developed AKI (5.8 %). The median sCr increase was 0.4 (interquartile range 0.3–0.6) mg/dL. Independent patient factors associated with increased risk included higher body mass index [odds ratio (OR) 1.24, 95 % CI 1.06–1.46 per 5 unit increase, P  = 0.01] and medically treated diabetes mellitus (OR 2.77, 1.36–5.65, P  = 0.01). Patients experiencing AKI had higher rates of blood transfusions ( P  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-012-0766-1