Building phylogenetic trees by using gene Nucleotide Genomic Signals

Nucleotide genomic signal (NuGS) methodology allows a molecular level approach to determine distances between homologous genes or between conserved equivalent non-coding genome regions in various species or individuals of the same species. Therefore, distances between the genes of species or individ...

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Bibliographic Details
Published in:2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2012-01, Vol.2012, p.5549-5553
Main Author: Cristea, P. D.
Format: Article
Language:English
Subjects:
Bioinformatics
DNA
Genomics
Immune system
Phylogeny
Signal processing
Online Access:Request full text
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Summary:Nucleotide genomic signal (NuGS) methodology allows a molecular level approach to determine distances between homologous genes or between conserved equivalent non-coding genome regions in various species or individuals of the same species. Therefore, distances between the genes of species or individuals can be computed and phylogenetic trees can be built. The paper illustrates the use of the nucleotide imbalance (N) and nucleotide pair imbalance (P) signals to determine the distances between the genes of several Hominidae. The results are in accordance with those of other genetic or phylogenetic approaches to establish distances between Hominidae species.
ISSN:1094-687X
1558-4615
2694-0604
DOI:10.1109/EMBC.2012.6347251