An investigation of simultaneous variations in cerebral blood flow velocity and arterial blood pressure during Sleep Apnea

Obstructive Sleep Apnea (OSA) is a major sleep disorder with a prevalence of about 15 % among US adult population and can lead to cardiovascular diseases and stroke. In this study, we have investigated the OSA-induced concurrent rise in cerebral blood flow velocity and blood pressure in 5 positively...

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Bibliographic Details
Published in:2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2012-01, Vol.2012, p.5634-5637
Main Authors: Alex, R., Bhave, G., Al-Abed, M. A., Bashaboyina, A., Iyer, S., Watenpaugh, D. E., Rong Zhang, Behbehani, K.
Format: Article
Language:English
Subjects:
Arterial blood pressure
Biomedical monitoring
Blood
Blood flow
Correlation
Sleep apnea
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Summary:Obstructive Sleep Apnea (OSA) is a major sleep disorder with a prevalence of about 15 % among US adult population and can lead to cardiovascular diseases and stroke. In this study, we have investigated the OSA-induced concurrent rise in cerebral blood flow velocity and blood pressure in 5 positively diagnosed sleep apnea subjects. The subject population had a mean AHI of 57.94±25.73 and BMI of 33.66±7.27 kg/m 2 . The results of this preliminary study yielded a relatively high correlation between rise in blood pressure and rise in cerebral blood flow velocity during apnea episodes (r=0.61±0.16) compared to normal breathing (r=0.28±0.26). These findings suggest that cerebral autoregulation may be less effective during apnea episodes.
ISSN:1094-687X
1558-4615
2694-0604
DOI:10.1109/EMBC.2012.6347272