Pregnancies in women with uterine malformation, treated obstruction of hemivagina and ipsilateral renal agenesis

Purpose The aim of this study was to evaluate the outcome of pregnancies in women who had uterine malformation and surgically treated obstructed hemivagina with ipsilateral renal agenesis. Methods The study group comprised 21 women with malformed uterus (12 didelphic, 6 septate and 3 bicornuate uter...

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Bibliographic Details
Published in:Archives of gynecology and obstetrics 2013-05, Vol.287 (5), p.975-978
Main Author: Heinonen, Pentti K.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Child
Congenital Abnormalities
Endocrinology
Female
General Gynecology
Gestational Age
Gynecology
Hematocolpos - etiology
Hematocolpos - surgery
Human Genetics
Humans
Kidney - abnormalities
Kidney Diseases - complications
Kidney Diseases - congenital
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Preeclampsia
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Treatment Outcome
Uterus - abnormalities
Vagina - abnormalities
Vagina - surgery
Vaginal Diseases - surgery
Young Adult
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Summary:Purpose The aim of this study was to evaluate the outcome of pregnancies in women who had uterine malformation and surgically treated obstructed hemivagina with ipsilateral renal agenesis. Methods The study group comprised 21 women with malformed uterus (12 didelphic, 6 septate and 3 bicornuate uterus). All of them had a history of surgical excision of the longitudinal vaginal septum caused obstructed hemivagina and ipsilateral renal agenesis. All pregnancies and possible surgical interventions were evaluated during the follow-up period (median 13.2 years). Results Thirteen out of 21 women attempting pregnancy conceived. They produced 22 pregnancies, 17 (77 %) were contralateral to the treated obstructed hemivagina and unilateral renal agenesis. The median interval between surgical treatment of obstructed hemivagina and the first pregnancy was 10.5 years. Twenty (91 %) pregnancies ended in delivery of a living infant. Preeclampsia (14 %), preterm delivery (36 %), high frequency (38 %) of fetal breech presentation and the cesarean section rate (67 %) were found. Conclusions Accurate diagnosis and appropriate surgery to open an obstructed hemivagina in adolescence assure fertility. Preterm birth is associated with malformed uterus and unilateral renal agenesis may predispose to preeclampsia.
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-012-2680-0