Case-control study of Staphylococcus lugdunensis infection isolates from small companion animals

Background –  Coagulase‐negative Staphylococcus lugdunensis has recently been shown to cause invasive infections of people, which are similar in pathogenic effect to those caused by Staphylococcus aureus. Little is known about the pathogenicity of S. lugdunensis in companion animals. Objectives –  T...

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Bibliographic Details
Published in:Veterinary dermatology 2012-12, Vol.23 (6), p.476-e90
Main Authors: Rook, Kathryn A., Brown, Dorothy C., Rankin, Shelley C., Morris, Daniel O.
Format: Article
Language:English
Subjects:
Animals
Case-Control Studies
Cat Diseases - microbiology
Cats
Chinchilla
Dog Diseases - microbiology
Dogs
Female
Glucocorticoids - administration & dosage
Guinea Pigs
Male
Retrospective Studies
Risk Factors
Rodent Diseases - microbiology
Staphylococcal Skin Infections - microbiology
Staphylococcal Skin Infections - veterinary
Staphylococcus aureus
Staphylococcus lugdunensis
Staphylococcus lugdunensis - isolation & purification
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Summary:Background –  Coagulase‐negative Staphylococcus lugdunensis has recently been shown to cause invasive infections of people, which are similar in pathogenic effect to those caused by Staphylococcus aureus. Little is known about the pathogenicity of S. lugdunensis in companion animals. Objectives –  To compare potential risk factors for infection, body sites affected, and whether cases and controls had been treated with antimicrobial drugs based upon susceptibility test results. Animals –  Thirty‐three cases of S. lugdunensis infection (25 dogs, six cats and two small mammals) were identified between January 2003 and August 2011. Two Staphylococcus pseudintermedius controls, which were identified by the microbiology laboratory immediately before and after each S. lugdunensis case, were host‐species matched to each case. Methods –  A retrospective case–control analysis. Results –  During the period evaluated, the prevalence of S. lugdunensis infection was 1.3 cases per 10,000 hospital admissions for dogs and 0.95 cases per 10,000 admissions for cats (P = 0.453). In univariate analyses, S. pseudintermedius isolation was significantly associated with skin infections (P 
ISSN:0959-4493
1365-3164
DOI:10.1111/j.1365-3164.2012.01087.x