Left Ventricular Mass Index and Its Relationship to Ambulatory Blood Pressure and Renal Resistivity Index in Renal Transplant Recipients

Abstract Introduction and Aims Left ventricular hypertrophy (LVH) is frequently observed in patients with end-stage renal disease and renal allograft recipients. It is an independent, strong predictor of morbidity and mortality. Renal resistive index (RRI) is an important determinant of graft functi...

Full description

Saved in:
Bibliographic Details
Published in:Transplantation proceedings 2013-05, Vol.45 (4), p.1575-1578
Main Authors: Sezer, S, Uyar, M.E, Çolak, T, Bal, Z, Tutal, E, Kalaci, G, Acar, F.N.Ö
Format: Article
Language:English
Subjects:
Adult
Blood Pressure Monitoring, Ambulatory
Female
Heart Ventricles - diagnostic imaging
Heart Ventricles - pathology
Humans
Kidney - physiopathology
Kidney Transplantation
Male
Middle Aged
Organ Size
Surgery
Ultrasonography, Doppler
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Introduction and Aims Left ventricular hypertrophy (LVH) is frequently observed in patients with end-stage renal disease and renal allograft recipients. It is an independent, strong predictor of morbidity and mortality. Renal resistive index (RRI) is an important determinant of graft function in transplant recipients. In essential hypertension, increased RRI is associated with reduced renal function and tubulointerstitial damage. In this present study, we investigated the association of ambulatory blood pressure monitoring parameters and RRI on left ventricular mass index among renal transplant recipients. Methods Charts of 98 renal transplant recipients with echocardiography, ambulatory blood pressure monitoring, and renal Doppler ultrasonography as well as laboratory tests including serum creatinine, glomerular filtration rate, and C-reactive protein (CRP) level at the end of post-transplantation year 1 were analyzed in this study. LVMI was calculated using the Devereux formula with echocardiographic findings. Results Left ventricular mass index (LVMI) positively correlated with mean systolic blood pressure (SBP) ( r = 0.512; P = .0001), mean nighttime SBP ( r = 0.312; P = .007), mean nighttime diastolic blood pressure (DBP) ( r = 0.427; P = .005), renal resistive index (RRI; r = 0.290; P = .004), and age ( r = 0.371; P = .001). Multiple logistic regression analysis revealed that mean and maximum nighttime SBP and RRI were independent risk factors for LVMI ( P = .001, .035, and .05, respectively). Conclusion High RRI is one of the main indicators of cardiovascular disease in renal transplant recipients. Additionally, older age, high blood pressure, and nondipper pattern are important risk factors of LVH.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2013.01.105