Propionibacterium acnes delayed infection following spinal surgery with instrumentation

• Published in: Musculoskeletal surgery 2013-04, Vol.97 (1), p.85-87
• Main Authors: Mhaidli, Hani H., Der-Boghossian, Asdghig H., Haidar, Rachid K.
• Format: Article
• Language: English
• Subjects: Acne; Aged; Anti-Bacterial Agents - therapeutic use; Case Report; Ciprofloxacin - therapeutic use; Delayed Diagnosis; Disease Progression; Fistula - diagnosis; Fistula - microbiology; Fistula - therapy; Follow-Up Studies; Gram-Positive Bacterial Infections - complications; Gram-Positive Bacterial Infections - diagnosis; Gram-Positive Bacterial Infections - microbiology; Gram-Positive Bacterial Infections - therapy; Health aspects; Humans; Infection; Male; Medicine; Medicine & Public Health; Neurosurgical Procedures - adverse effects; Neurosurgical Procedures - methods; Orthopedic surgery; Orthopedics; Propionibacterium acnes; Propionibacterium acnes - isolation & purification; Spinal Fractures - surgery; Surgical Orthopedics; Surgical Wound Infection - diagnosis; Surgical Wound Infection - microbiology; Surgical Wound Infection - therapy; Thoracic Vertebrae - surgery; Treatment Outcome
• ISSN: 2035-5106; 2035-5114
• DOI: 10.1007/s12306-012-0183-6

Propionibacterium acnes detection in culture media was previously considered a contamination but recently its infectious role was discovered in post-spinal surgery infections. P. acnes might be introduced during surgery. Its diagnosis is based on non-specific clinical signs, image indications of infection, and the conclusive microbiological sign. Furthermore, its diagnosis is difficult because of slow growth rate and low virulence, delaying its presentation. Usually, the infection is manifested after a couple of months or years. Here, a 65-year-old man presented with drainage at the site of instrumented spinal surgery performed 13 years ago. P. acnes infection was confirmed by culture with extended incubation. Our review of the literature revealed only two other reported cases of delayed P. acnes infection presenting a decade following a spinal surgery with instrumentation. This article sheds light on such delayed infections and discusses their presentation and management.