Negative Symptoms of Schizophrenia Are Associated with Abnormal Effort-Cost Computations

Decision-making studies show that response selection is influenced by the “effort cost” associated with response alternatives. These effort-cost calculations seem to be mediated by a distributed neural circuit including the anterior cingulate cortex and subcortical targets of dopamine neurons. On th...

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Published in:Biological psychiatry (1969) 2013-07, Vol.74 (2), p.130-136
Main Authors: Gold, James M., Strauss, Gregory P., Waltz, James A., Robinson, Benjamin M., Brown, Jamie K., Frank, Michael J.
Format: Article
Language:English
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