Diffusion-weighted magnetic resonance imaging evaluation of intra-abdominal sites of implants to predict likelihood of suboptimal cytoreductive surgery in patients with ovarian carcinoma

Objectives To analyse the diagnostic accuracy and to establish a predictive score based on diffusion-weighted magnetic resonance imaging (DWMRI) compared to exploratory laparotomy (EL) for predicting suboptimal cytoreductive surgery for different intra-abdominal sites of implants in patients with ov...

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Bibliographic Details
Published in:European radiology 2013-09, Vol.23 (9), p.2636-2642
Main Authors: Espada, Mercedes, Garcia-Flores, Jose R., Jimenez, Mar, Alvarez-Moreno, Elena, De Haro, Mar, Gonzalez-Cortijo, Lucia, Hernandez-Cortes, Gines, Martinez-Vega, Vicente, Sainz De La Cuesta, Ricardo
Format: Article
Language:English
Subjects:
Abdomen
Abdomen - pathology
Accuracy
Adult
Aged
Brachytherapy - methods
Cancer therapies
Carcinoma - pathology
Carcinoma - radiotherapy
Carcinoma - surgery
Chemotherapy
Diagnostic Radiology
Diffusion Magnetic Resonance Imaging - methods
Female
Gynecology
Hospitals
Humans
Imaging
Internal Medicine
Interventional Radiology
Laparotomy
Magnetic resonance imaging
Medical prognosis
Medicine
Medicine & Public Health
Mesentery
Middle Aged
Neuroradiology
Oncology
Ovarian cancer
Ovarian Neoplasms - pathology
Ovarian Neoplasms - radiotherapy
Ovarian Neoplasms - surgery
Patients
Pelvis
Predictive Value of Tests
Radiology
Reference Values
Reproducibility of Results
ROC Curve
Sensitivity and Specificity
Surgery
Surgical outcomes
Treatment Outcome
Ultrasound
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Summary:Objectives To analyse the diagnostic accuracy and to establish a predictive score based on diffusion-weighted magnetic resonance imaging (DWMRI) compared to exploratory laparotomy (EL) for predicting suboptimal cytoreductive surgery for different intra-abdominal sites of implants in patients with ovarian cancer. Methods Thirty-four patients with advanced ovarian carcinoma were studied. Preoperative DWMRI of the abdomen and pelvis was performed. DWMRI findings were compared with EL. Ten anatomical sites were selected for inclusion in the score. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy for suboptimal cytoreduction were calculated for both DWMRI and EL. Receiver operating characteristic (ROC) curve analysis was used to assess the ability to predict suboptimal cytoreduction. Results Using predictive score, ROC curves were generated with an area under the curve of 0.938 for DWMRI and 0.947 for EL ( P  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-013-2837-7