Urinary excretion of hydroxy-phenanthrenes after intake of polycyclic aromatic hydrocarbons

The intake of polycyclic aromatic hydrocarbons (PAH) from various sources including smoking, passive smoking, diet, and workplace was studied. Up to five different monohydroxy-phenanthrenes (OH-PHE) excreted into the urine were used as biomarkers for PAH exposure. The OH-PHE excretion of smokers was...

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Bibliographic Details
Published in:Environment international 1989, Vol.15 (1), p.41-47
Main Authors: Martin, F., Hoepfner, I., Scherer, G., Adlkofer, F., Dettbarn, G., Grimmer, G.
Format: Article
Language:English
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Summary:The intake of polycyclic aromatic hydrocarbons (PAH) from various sources including smoking, passive smoking, diet, and workplace was studied. Up to five different monohydroxy-phenanthrenes (OH-PHE) excreted into the urine were used as biomarkers for PAH exposure. The OH-PHE excretion of smokers was slightly but not significantly elevated as compared to nonsmokers. No difference in urinary OH-PHE excretion was observed in nonsmokers before and after exposure to enviromental tobacco smoke (ETS) even if the exposure levels were unrealistically high. A diet containing elevated levels of PAH leads to a rise in urinary OH-PHE excretion. A considerable increase in OH-PHE excretion was found in road paving workers as well as in one wood creosoting worker. The amount of OH-PHE excreted was up to 200 times higher than in nonsmoking or smoking controls.
ISSN:0160-4120
1873-6750
DOI:10.1016/0160-4120(89)90008-1