Non-transplant surgery for short bowel syndrome

• Published in: Pediatric surgery international 2013-10, Vol.29 (10), p.983-987
• Main Author: Millar, Alastair J. W.
• Format: Article
• Language: English
• Subjects: Digestive System Surgical Procedures; Enteral Nutrition - methods; Humans; Medicine; Medicine & Public Health; Parenteral Nutrition - methods; Pediatric Surgery; Pediatrics; Review Article; Short Bowel Syndrome - therapy; Surgery
• ISSN: 0179-0358; 1437-9813
• DOI: 10.1007/s00383-013-3390-9

The goal of any treatment programme for short bowel syndrome SBS is to achieve nutritional enteral autonomy. This must begin with conservation of as much bowel as possible from the time of first presentation. Frequent causes of the short bowel syndrome are intestinal atresia, necrotizing enterocolitis, midgut volvulus, extended intestinal aganglionosis, ‘vanished gut’ often associated with gastroschisis and occasionally catastrophic trauma. Atresia is more amenable to successful surgery than other causes, except when associated with gastroschisis. Intrinsic dysmotility has a poor prognosis. Intestinal lengthening procedures are only indicated if there is sufficient bowel dilatation. Extended intestinal aganglionosis is rarely amenable to any form of non-transplant surgery. Options available are to conserve bowel, close stomas early (use all available bowel to the maximum or even re-feed stoma effluent into the distal unused bowel), release adhesions causing obstruction, resect strictures, taper or excise localized dilatations and finally address dilated bowel with lengthening and tailoring operations. These procedures aim to improve effective peristalsis, thereby reducing bacterial overgrowth and improving nutrient contact with enteral mucosa to maximize absorption and intestinal adaptation. The Bianchi longitudinal splicing operation and the serial transverse enteroplasty operations have stood the test of time in providing considerable improvement in enteral nutritional autonomy in around 60 % of cases. In SBS without dilatation attempts at ‘mechanically’ delaying transit (nipple valves, reversed bowel segments, colon interposition) have had inconsistent outcomes. Growing neomucosa and lengthening bowel by longitudinal stretch are still experimental.