Oxygenation and ventilation characteristics in obese sedated dogs before and after weight loss: A clinical trial

This prospective clinical study examined the effect of obesity and subsequent weight loss on oxygenation and ventilation during deep sedation in pet dogs. Data from nine dogs completing a formalised weight loss programme were evaluated. Dual-energy X-ray absorptiometry (DEXA) was used to quantify bo...

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Bibliographic Details
Published in:The veterinary journal (1997) 2013-11, Vol.198 (2), p.367-371
Main Authors: Mosing, M., German, A.J., Holden, S.L., MacFarlane, P., Biourge, V., Morris, P.J., Iff, I.
Format: Article
Language:English
Subjects:
Absorptiometry, Photon - veterinary
Adipose Tissue - metabolism
Animals
Blood Gas Analysis - veterinary
Carbon Dioxide - blood
Deep Sedation - veterinary
Dog
Dog Diseases - etiology
Dog Diseases - physiopathology
Dogs
Dual-energy X-ray absorptiometry (DEXA)
Female
Male
Obesity
Obesity - etiology
Obesity - physiopathology
Obesity - veterinary
Oximetry - veterinary
Oxygen - blood
Oxygen indices
Partial Pressure
Prospective Studies
Pulmonary Ventilation
Sedation
Ventilation
Weight Loss
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Summary:This prospective clinical study examined the effect of obesity and subsequent weight loss on oxygenation and ventilation during deep sedation in pet dogs. Data from nine dogs completing a formalised weight loss programme were evaluated. Dual-energy X-ray absorptiometry (DEXA) was used to quantify body fat mass prior to and after weight loss. Dogs were deeply sedated and positioned in dorsal recumbency. Sedation was scored using a semi-objective scheme. As part of the monitoring of sedation, arterial oxygen partial pressure (PaO2) and arterial carbon dioxide partial pressure (PaCO2) were measured after 10min in dorsal recumbency. Oxygen saturation of haemoglobin (SpO2) was monitored continuously using pulse oximetry, starting oxygen supplementation where indicated (SpO2
ISSN:1090-0233
1532-2971
DOI:10.1016/j.tvjl.2013.08.008