Laryngopharyngeal reflux and GERD

In patients with laryngopharygeal reflux (LPR), gastric contents exhibit retrograde flow into the upper aero‐digestive tract, causing extraesophageal symptoms including chronic cough, hoarseness, indigestion, difficulty swallowing, globus pharyngis, and asthma. The following on laryngopharyngeal ref...

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Bibliographic Details
Published in:Annals of the New York Academy of Sciences 2013-10, Vol.1300 (1), p.71-79
Main Authors: Johnston, Nikki, Dettmar, Peter W., Strugala, Vicki, Allen, Jacqui E., Chan, Walter W.
Format: Article
Language:English
Subjects:
Antibodies
Cancer
Cough
Cough - etiology
Cough - physiopathology
Deglutition Disorders - etiology
Deglutition Disorders - physiopathology
Diagnosis
diagnostic tests
Gastroesophageal Reflux - complications
Gastroesophageal Reflux - diagnosis
Gastroesophageal Reflux - physiopathology
Hoarseness - etiology
Hoarseness - physiopathology
Humans
Inhibitors
laryngeal cancer
Laryngopharyngeal Reflux - complications
Laryngopharyngeal Reflux - diagnosis
Laryngopharyngeal Reflux - physiopathology
larynopharyngeal reflux
Pepsin
proton pump inhibitor
Pumps
Swallowing
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Summary:In patients with laryngopharygeal reflux (LPR), gastric contents exhibit retrograde flow into the upper aero‐digestive tract, causing extraesophageal symptoms including chronic cough, hoarseness, indigestion, difficulty swallowing, globus pharyngis, and asthma. The following on laryngopharyngeal reflux includes commentaries on the use of patient‐completed questionaires and anti‐human pepsin antibodies and other non‐invasive tests in diagnosis; the role of pepsin and acid in the etiologies of laryngeal cancers; and the application of proton pump inhibitor (PPI) therapy for the treatment of LPR.
ISSN:0077-8923
1749-6632
DOI:10.1111/nyas.12237