Depressive syndromes in neurological disorders

Depressive syndromes represent a common and often characteristic feature in a number of neurological disorders. One prominent example is the development of post-stroke depression, which can be observed in more than one-third of stroke survivors in the aftermath of an ischemic stroke. Thus, post-stro...

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Bibliographic Details
Published in:European archives of psychiatry and clinical neuroscience 2013-11, Vol.263 (Suppl 2), p.123-136
Main Authors: Hellmann-Regen, Julian, Piber, Dominique, Hinkelmann, Kim, Gold, Stefan M., Heesen, Christoph, Spitzer, Carsten, Endres, Matthias, Otte, Christian
Format: Article
Language:English
Subjects:
Depressive Disorder - epidemiology
Depressive Disorder - etiology
Depressive Disorder - psychology
Depressive Disorder - therapy
Epilepsy - complications
Epilepsy - epidemiology
Epilepsy - psychology
Humans
Medicine
Medicine & Public Health
Multiple Sclerosis - complications
Multiple Sclerosis - epidemiology
Multiple Sclerosis - psychology
Nervous System Diseases - complications
Nervous System Diseases - epidemiology
Nervous System Diseases - psychology
Nervous System Diseases - therapy
Neurological disorders
Neurosciences
Parkinson Disease - complications
Parkinson Disease - epidemiology
Parkinson Disease - psychology
Psychiatry
Review
Risk Factors
Stroke - complications
Stroke - epidemiology
Stroke - psychology
Systematic review
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Summary:Depressive syndromes represent a common and often characteristic feature in a number of neurological disorders. One prominent example is the development of post-stroke depression, which can be observed in more than one-third of stroke survivors in the aftermath of an ischemic stroke. Thus, post-stroke depression represents one of the most prevalent, disabling, and potentially devastating psychiatric post-stroke complications. On the other hand, depressive syndromes may also be considered as a risk factor for certain neurological disorders, as recently revealed by a meta-analysis of prospective cohort studies, which demonstrated an increased risk for ischemic events in depressed patients. Moreover, depressive syndromes represent common comorbidities in a number of other neurological disorders such as Parkinson’s disease, multiple sclerosis, or epilepsy, in which depression has a strong impact on both quality of life and outcome of the primary neurological disorder.
ISSN:0940-1334
1433-8491
DOI:10.1007/s00406-013-0448-6