Loading…
Longitudinal Study of Liver Transplant Recipients' Quality of Life as a Function of Their Perception of General Health: At Waiting List and at 3, 6, and 12 Months Post-Transplantation
Abstract Objective The objective of this study was to compare the evolution (at waiting list, and at 3, 6, and 12 months post-transplantation) of quality of life of cadaveric liver transplant recipients as a function of their perception of general health. Methods Two groups (15 patients with better...
Saved in:
Published in: | Transplantation proceedings 2013-12, Vol.45 (10), p.3653-3655 |
---|---|
Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | Abstract Objective The objective of this study was to compare the evolution (at waiting list, and at 3, 6, and 12 months post-transplantation) of quality of life of cadaveric liver transplant recipients as a function of their perception of general health. Methods Two groups (15 patients with better and 15 with worse self-perception of health 1 year after transplantation) were assessed at the pretransplantation and post-transplantation phases using the EuroQol (EQ-5D) questionnaire. Mixed analysis of covariance was performed with 2 factors: phase (at waiting list and at 3, 6, and 12 months post-transplantation) and perception of general health (better and worse). Cohen’s d was also calculated. Results Interactive effects were found in the variables pain/discomfort ( P = .010) and anxiety/depression ( P = .001). The following simple effects reached large effect sizes. Transplant recipients presented more pain/discomfort when on the waiting list than at 3 months (worse self-perception, P = .022, d = 1.35; better self-perception, P = .001, d = 0.95). At 6 months ( P = .001, d = −1.45) and at 12 months ( P = .001, d = −1.75), transplant recipients with worse self-perception displayed more pain/discomfort. Transplant recipients with better self-perceived health showed more anxiety/depression when on the waiting list than at 3 months ( P = .004, d = 1.49), at 6 months ( P = .005, d = 1.48), and at 12 months ( P = .001, d = 1.97). Patients with worse self-perception presented more anxiety/depression when on the waiting list than at 6 months ( P = .030, d = 1.21) and 12 months compared with at 3 months ( P = .011, d = −0.97) and 6 months ( P = .001, d = −1.39). At 12 months, transplant recipients with worse self-perception showed more anxiety/depression ( P = .001, d = −2.18). Conclusion Pain/discomfort and, especially, anxiety/depression contribute to liver transplant recipients' worse general health status 1 year after transplantation. |
---|---|
ISSN: | 0041-1345 1873-2623 |
DOI: | 10.1016/j.transproceed.2013.10.026 |