Evidence-Based Treatment of Post-Traumatic Stress Disorder

The term translational research is typically used to refer both to "bench to bedside" research, in which preclinical research findings inform the development of novel therapeutics, and to the dissemination of new treatments to the community to encourage the use of the new health practices...

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Bibliographic Details
Published in:Annual review of medicine 2014-01, Vol.65 (1), p.319-332
Main Authors: Difede, JoAnn, Olden, Megan, Cukor, Judith
Format: Article
Language:English
Subjects:
Anti-Anxiety Agents - therapeutic use
anxiety
cognitive behavioral therapy
Evidence-Based Medicine
fear conditioning
Humans
Mental health care
Post traumatic stress disorder
Psychotherapy
Serotonin Uptake Inhibitors - therapeutic use
stress disorders
Stress Disorders, Post-Traumatic - therapy
trauma
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Summary:The term translational research is typically used to refer both to "bench to bedside" research, in which preclinical research findings inform the development of novel therapeutics, and to the dissemination of new treatments to the community to encourage the use of the new health practices and treatments. Both definitions are germane to understanding the evidence base for treatment of post-traumatic stress disorder (PTSD) today. This article offers ( a ) an overview of evidence-based treatments for PTSD, ( b ) a description of a translational model of PTSD, and ( c ) a discussion of common barriers to dissemination and implementation of the empirically validated treatments. Recent studies in the field are discussed with a focus on pharmacotherapies, psychotherapies, and combined treatments.
ISSN:0066-4219
1545-326X
DOI:10.1146/annurev-med-051812-145438