Factors Affecting Survival in Men Versus Women Following Transcatheter Aortic Valve Implantation

Although transcatheter aortic valve implantation (TAVI) for severe aortic stenosis is becoming an established technique, the impact of gender-related differences remains unclear. Two hundred twenty-four consecutive patients undergoing TAVI were prospectively followed up in a tertiary medical center....

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Bibliographic Details
Published in:The American journal of cardiology 2014-02, Vol.113 (4), p.701-705
Main Authors: Erez, Aharon, MD, Segev, Amit, MD, Medvedofsky, Diego, MD, Fefer, Paul, MD, Raanani, Ehud, MD, Goldenberg, Ilan, MD, Guetta, Victor, MD
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aortic Valve - surgery
Aortic Valve Stenosis - mortality
Aortic Valve Stenosis - surgery
Cardiac Catheterization - mortality
Cardiology
Cardiovascular
Coronary vessels
Female
Follow-Up Studies
Heart attacks
Heart Valve Prosthesis Implantation - mortality
Humans
Male
Men
Mortality
Prospective Studies
Risk Assessment
Risk Factors
Sex Factors
Survival Analysis
Survival Rate
Treatment Outcome
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Summary:Although transcatheter aortic valve implantation (TAVI) for severe aortic stenosis is becoming an established technique, the impact of gender-related differences remains unclear. Two hundred twenty-four consecutive patients undergoing TAVI were prospectively followed up in a tertiary medical center. The primary end point of the present study was all-cause mortality at 2 years of follow-up. Interaction-term analysis was used to identify gender-specific predictors of mortality after TAVI. Fifty-seven percent of the study patients were women. Age was similar (82 ± 7 years). Compared with men, women had a lower frequency of coronary artery disease (CAD) and a higher baseline left ventricular ejection fraction (LVEF). The cumulative probability of all-cause mortality was significantly lower among women (8.6%) compared with men (26.8%; log-rank p value
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2013.10.047