Nanotechnological Advances in Cutaneous Medicine

Wound healing is an area of unmet clinical need. Current treatments include occlusive dressings, hydrogels, and antimicrobials to control infection. However with the growing number of antibiotic-resistant bacteria and the increase in population age and clinical obesity, it is becoming proportionally...

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Bibliographic Details
Published in:Journal of nanomaterials 2013-01, Vol.2013 (2013), p.1-8
Main Authors: Jackson, Jessica E., Cowin, Allison J., Kopecki, Zlatko
Format: Article
Language:English
Subjects:
Bacteria
Drug delivery systems
Lipids
Nanomaterials
Nanotechnology
Wound healing
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Summary:Wound healing is an area of unmet clinical need. Current treatments include occlusive dressings, hydrogels, and antimicrobials to control infection. However with the growing number of antibiotic-resistant bacteria and the increase in population age and clinical obesity, it is becoming proportionally harder to treat wounds with the drugs that have worked in the past. There is an urgent requirement for efficient mechanism-based treatments and more efficacious drug delivery systems. The potential of using nanoparticles as a drug delivery system has been identified and investigated. Nanoparticles have the ability to protect and carry drugs to specific targets in the body, enabling slower degradation, enhancing drug penetration, improving treatment efficacy with lower systemic absorption, and reducing unwanted side effects. Here we discuss the advantages and limitations of nanotechnology for the treatment of wounds and other cutaneous disorders.
ISSN:1687-4110
1687-4129
DOI:10.1155/2013/808234